OK, I did that (posted below) BUT, before you read the test results, be advised of the following.
I did a tiny bit more testing (with Word) before you responded and I discovered that the extreme delay occurs only the first time that I open the application after logon. If I quit Word and then double-click the document, it's a snappy five seconds! The MBP is consistently ten seconds under all circumstances. I no longer own the old iMac so I'm unable to check that one. While I do feel a bit better, there is still something weird with the new iMac.
In any event, I logged off and logged back on and then ran the Etre test. I don't know how to interpret the results. I'm hoping that you do.
EtreCheck version: 3.4.6 (460)
Report generated 2018-02-05 21:42:45
Download EtreCheck from https://etrecheck.com
Runtime: 2:34
Performance: Excellent
Click the [Lookup] links for more information from Apple Support Communities.
Click the [Details] links for more information about that line.
Problem: Computer is too slow
Hardware Information:ⓘ
iMac (Retina 4K, 21.5-inch, 2017)
[Technical Specifications] - [User Guide] - [Warranty & Service]
iMac - model: iMac18,2
1 3.4 GHz Intel Core i5 (i5-7500) CPU: 4-core
8 GB RAM Upgradeable - [Instructions]
BANK 0/DIMM0
4 GB DDR4 2400 MHz ok
BANK 1/DIMM0
4 GB DDR4 2400 MHz ok
Handoff/Airdrop2: supported
Wireless: en1: 802.11 a/b/g/n/ac
iCloud Quota: 4.68 GB available
Video Information:ⓘ
Radeon Pro 560 - VRAM: 4 GB
iMac 4096 x 2304
Disk Information:ⓘ
APPLE HDD HTS541010A9E632 disk0: (1 TB) (Rotational)
[Show SMART report]
EFI (disk0s1 - MS-DOS FAT32) <not mounted> [EFI]: 210 MB
(disk0s2) <not mounted> [CoreStorage Container]: 999.35 GB
Recovery HD (disk0s3 - HFS+) <not mounted> [Recovery]: 650 MB
APPLE SSD SM0032L disk1: (28 GB) (Solid State - TRIM: Yes)
(disk1s1) <not mounted> [EFI]: 315 MB
(disk1s2) <not mounted> [CoreStorage Container]: 27.55 GB
(disk1s3) <not mounted> [Boot]: 134 MB
USB Information:ⓘ
USB31Bus
LaCie P9227 Slim
P9227 Slim disk4: (1 TB)
EFI (disk4s1 - MS-DOS FAT32) <not mounted> [EFI]: 210 MB
Backup (disk4s2 - HFS+) /Volumes/Backup : 999.86 GB (614.46 GB free)
LaCie P9227 Slim
P9227 Slim disk3: (1 TB)
EFI (disk3s1 - MS-DOS FAT32) <not mounted> [EFI]: 210 MB
Photos (disk3s2 - Journaled HFS+) /Volumes/Photos : 999.86 GB (899.65 GB free)
USB30Bus
Broadcom Corp. Bluetooth USB Host Controller
Apple Inc. FaceTime HD Camera (Built-in)
Canon CanoScan
Fitbit Inc. Fitbit Base Station
Canon iP4900 series
Thunderbolt Information:ⓘ
Apple Inc. thunderbolt_bus
Virtual disks:ⓘ
Macintosh HD (disk2 - Journaled HFS+) / [Startup]: 1.03 TB (811.68 GB free)
Physical disk: disk1s2 27.55 GB Online
Physical disk: disk0s2 999.35 GB Online
System Software:ⓘ
macOS High Sierra 10.13.3 (17D47) - Time since boot: about 6 days
Gatekeeper:ⓘ
Mac App Store and identified developers
Kernel Extensions:ⓘ
/Library/Extensions
[loaded] com.malwarebytes.mbam.rtprotection (3.1 - SDK 10.12) [Lookup]
System Launch Agents:ⓘ
[not loaded] 8 Apple tasks
[loaded] 178 Apple tasks
[running] 104 Apple tasks
System Launch Daemons:ⓘ
[not loaded] 34 Apple tasks
[loaded] 169 Apple tasks
[running] 127 Apple tasks
Launch Agents:ⓘ
[running] com.adobe.AdobeCreativeCloud.plist (Adobe Systems, Inc. - installed 2017-09-26) [Lookup]
[not loaded] com.adobe.GC.Invoker-1.0.plist (Adobe Systems, Inc. - installed 2018-01-25) [Lookup]
[loaded] com.google.keystone.agent.plist (Google, Inc. - installed 2017-09-27) [Lookup]
[running] com.malwarebytes.mbam.frontend.agent.plist (Malwarebytes Corporation - installed 2017-11-08) [Lookup]
[loaded] com.microsoft.update.agent.plist (Microsoft Corporation - installed 2018-01-25) [Lookup]
Launch Daemons:ⓘ
[loaded] com.adobe.acc.installer.plist (Adobe Systems, Inc. - installed 2017-09-26) [Lookup]
[running] com.adobe.agsservice.plist (Adobe Systems, Inc. - installed 2018-01-25) [Lookup]
[loaded] com.adobe.fpsaud.plist (Adobe Systems, Inc. - installed 2017-12-14) [Lookup]
[loaded] com.google.keystone.daemon.plist (Google, Inc. - installed 2017-10-13) [Lookup]
[loaded] com.malwarebytes.HelperTool.plist (Malwarebytes Corporation - installed 2017-03-04) [Lookup]
[running] com.malwarebytes.mbam.rtprotection.daemon.plist (Malwarebytes Corporation - installed 2017-11-08) [Lookup]
[running] com.malwarebytes.mbam.settings.daemon.plist (Malwarebytes Corporation - installed 2017-11-08) [Lookup]
[loaded] com.microsoft.autoupdate.helper.plist (Microsoft Corporation - installed 2018-01-25) [Lookup]
[loaded] com.microsoft.office.licensingV2.helper.plist (Microsoft Corporation - installed 2017-12-05) [Lookup]
User Launch Agents:ⓘ
[loaded] com.adobe.AAM.Updater-1.0.plist (Adobe Systems, Inc. - installed 2016-11-25) [Lookup]
[loaded] com.adobe.ARM.[...].plist (? 5c76f5f6 1c9bb8a9 - installed 2015-10-14) [Lookup]
[loaded] com.adobe.GC.Invoker-1.0.plist (Adobe Systems, Inc. - installed 2018-01-26) [Lookup]
[loaded] com.dropbox.DropboxMacUpdate.agent.plist (Dropbox, Inc. - installed 2017-08-10) [Lookup]
User Login Items:ⓘ
iTunesHelper Application (Apple, Inc. - installed 2018-01-23)
(/Applications/iTunes.app/Contents/MacOS/iTunesHelper.app)
Dropbox Application
(/Applications/Dropbox.app)
Mail Application - Hidden
(/Applications/Mail.app)
1Password Helper URL SMLoginItem - Hidden (Apple, Inc. - installed 2018-01-18)
(/Applications/1Password.app/Contents/Library/LoginItems/2BUA8C4S2C.com.agilebi ts.onepassword-osx-helper.app)
1Password Helper URL SMLoginItem - Hidden (Apple, Inc. - installed 2017-12-22)
(/Volumes/Backup/Backups.backupdb/[redacted]'s iMac/2017-12-26-203435/iMac HD/Applications/1Password.app/Contents/Library/LoginItems/2BUA8C4S2C.com.agileb its.onepassword-osx-helper.app)
Internet Plug-ins:ⓘ
AdobeAAMDetect: 3.0.0.0 (installed 2017-09-26) [Lookup]
FlashPlayer-10.6: 28.0.0.137 (installed 2018-01-10) [Lookup]
QuickTime Plugin: 7.7.3 (installed 2018-01-19)
AdobePDFViewerNPAPI: 10.1.16 (installed 2015-10-14) [Lookup]
AdobePDFViewer: 10.1.16 (installed 2015-10-14) [Lookup]
Flash Player: 28.0.0.137 (installed 2018-01-10) [Lookup]
OfficeLiveBrowserPlugin: 12.3.6 (installed 2014-02-05) [Lookup]
PepperFlashPlayer: 28.0.0.137 (installed 2018-01-09) [Lookup]
Safari Extensions:ⓘ
[not loaded] Adblock Plus - Eyeo GmbH - https://adblockplus.org/ (installed 2016-12-22)
[not loaded] WOT - WOT Services Ltd - http://www.mywot.com/ (installed 2016-04-22)
[enabled] Facebook Cleaner - Sonny Fazio - http://sonstermedia.com (installed 2014-03-15)
[enabled] 1Password - AgileBits - https://agilebits.com/onepassword (installed 2017-12-27)
3rd Party Preference Panes:ⓘ
Flash Player (installed 2017-12-14) [Lookup]
Time Machine:ⓘ
Skip System Files: NO
Mobile backups: OFF
Auto backup: YES
Volumes being backed up:
Macintosh HD: Disk size: 1.03 TB Disk used: 214.30 GB
Photos: Disk size: 999.86 GB Disk used: 100.21 GB
Destinations:
Backup [Local]
Total size: 999.86 GB
Total number of backups: 41
Oldest backup: 12/26/17, 8:34 PM
Last backup: 2/5/18, 9:20 PM
Size of backup disk: Adequate
Backup size 999.86 GB > (Disk used 314.51 GB X 3)
Top Processes by CPU:ⓘ
4% mds_stores
4% kernel_task
3% WindowServer
2% RTProtectionDaemon
2% Adobe CEF Helper
Top Processes by Memory:ⓘ
1.01 GB kernel_task
506 MB mds_stores
164 MB Adobe CEF Helper
157 MB identityservicesd
148 MB Dropbox
Top Processes by Network Use:ⓘ
Input Output Process name
27 MB 8 MB mDNSResponder
329 KB 220 KB netbiosd
63 KB 52 KB Dropbox
42 KB 47 KB apsd
23 KB 6 KB cloudd
Top Processes by Energy Use:ⓘ
4.78 WindowServer
3.40 mds
2.62 mdworker
2.60 mdworker
Virtual Memory Information:ⓘ
2.44 GB Available RAM
26 MB Free RAM
5.56 GB Used RAM
2.42 GB Cached files
453 MB Swap Used
Software installs (last 30 days):ⓘ
Adobe Flash Player: (installed 2018-01-09)
Adobe Pepper Flash Player: (installed 2018-01-09)
Adobe Flash Player: (installed 2018-01-10)
Universal Translator: 2.0.1 (installed 2018-01-10)
Translatium: 7.8.1 (installed 2018-01-10)
1Password: 6.8.6 (installed 2018-01-18)
Microsoft PowerPoint for Mac: (installed 2018-01-19)
Microsoft Outlook for Mac: (installed 2018-01-19)
Microsoft Excel for Mac: (installed 2018-01-19)
Microsoft OneNote for Mac: (installed 2018-01-19)
Microsoft Word for Mac: (installed 2018-01-19)
Banktivity: 6.3 (installed 2018-01-19)
Microsoft AutoUpdate: (installed 2018-01-25)
Battery Monitor: 2.4.3 (installed 2018-01-26)
Microsoft PowerPoint for Mac: (installed 2018-01-26)
Microsoft Word for Mac: (installed 2018-01-26)
OneDrive: 17.3.7294 (installed 2018-02-03)
Install information may not be complete.
Diagnostics Events (last 3 days for minor events):ⓘ
2018-02-04 12:14:09 SecurityAgent Crash [Open]
Cause: objc_msgSend() selector name: setResult: