MacOS High Sierra 10.13.3 additional update issue: normal shutdown or restart is no longer working on iMac

The initial macOS 10.13.3 update was executed correctly but the second additional update 10.13.3 requests a restart of the mac which does no longer seem to work.
A shutdown or restart now results into a black screen where the cursor gets repositioned at the left upper corner of my screen. You can still move the cursor but anything else is impossible.

It looks like macOS cannot shutdown the window server process.
The only option is to use the power button to shutdown or restart.

As the restart procedure does not seem to work correctly, even the 10.13.3 combo-update does not seem to execute.

There are a number of error in the logging in Console that also do not look ok 😟:

error 16:09:22.342002 +0100 lsd LaunchServices: _LSSchemaConfigureForStore failed with error -9499

error 16:09:22.342278 +0100 lsd LaunchServices: _LSDatabaseCreate failed with error -9499

error 16:09:22.342494 +0100 lsd LaunchServices: _LSDatabaseCreateFromPersistentStore Failed with error -10813

standard 16:09:22.356027 +0100 lsd <private>

error 16:09:22.372109 +0100 symptomsd LaunchServices: store or url (null) was nil -10813, retrying

error 16:09:22.372303 +0100 symptomsd LaunchServices: Database mapping failed with result -10813, retries = 0

The following is maybe normal because of the hard reset via the power button?

Process: gpg-agent [301]

Path: /usr/local/bin/gpg-agent

Identifier: gpg-agent

Version: ???

Code Type: X86 (Native)

Parent Process: launchd [1]

Responsible: gpg-agent [301]

User ID: 212

Date/Time: 2018-02-25 12:01:19.455 +0100

OS Version: Mac OS X 10.13.3 (17D47)

Report Version: 12

Anonymous UUID: 3C4874C0-A897-8911-AF76-C7BA5A817F3B

Time Awake Since Boot: 46 seconds

System Integrity Protection: enabled

Crashed Thread: 0

Exception Type: EXC_CRASH (SIGABRT)

Exception Codes: 0x0000000000000000, 0x0000000000000000

Exception Note: EXC_CORPSE_NOTIFY

Termination Reason: DYLD, [0x1] Library missing

Application Specific Information:

dyld: launch, loading dependent libraries

Dyld Error Message:

Library not loaded: /usr/local/lib/libgcrypt.11.dylib

Referenced from: /usr/local/bin/gpg-agent

Reason: image not found

Binary Images:

0x1000 - 0x46ff7 +gpg-agent (???) <16275973-06AF-B91B-7258-F1912B56D5BF> /usr/local/bin/gpg-agent

0xcc000 - 0x111fdf dyld (519.2.2) <7B7B05B7-204A-38FF-BD32-4CBB51752DD4> /usr/lib/dyld

Also not really ok seems (although correlation with 10.13.3 not clear):

Event: wakeups

Wakeups: 45001 wakeups over the last 295 seconds (153 wakeups per second average), exceeding limit of 150 wakeups per second over 300 seconds

System specs: macOS on iMac late 2011, Model iMac12,1, intel core i5