What is the best Mac cleaner software?

+3 for no cleaning software.

As the 2nd article points out, they are capable of regenerating after deletion with files that go to many parts of the system.

Safari/Browsers – can’t delete cookies

Evercookie

The myth of the dangerous cookie

Quit Safari.

In Finder go to Go menu and then Go to Folder.

Copy and paste this ~/Library/Safari/Databases.

Delete the contents of the folder.

Launch Safari again and check if all is ok.

If that doesn’t work, copy and paste this ~/Library/Safari/LocalStorage.

Delete the contents of the folder.

Then go to Safari/History and delete any entries for the related websites.

Test.

You do not need any of those. doniminc23 is correct. I wouldn't trust any of them.

There is a section on why you shouldn't install such things in this article:

Effective defenses against malware and other threats

Hello,

1. Cookies are created by web sites. There is no way to control or prevent that. You can try something like Cookie (https://cookie5app.com/) that will automatically remove non-favourite cookies on a regular basis.

2. Not all apps can be uninstalled by being dragged to the trash. Some of those "traces" are actually system files that were not created by the software in question and should not be deleted.

3. Recent versions of macOS already have features to manage your storage. Go to About this Mac > Storage > Manage.

Unfortunately, many popular "clean up" apps will damage your system.

Force quit Safari from the  menu and reopen with the shift key held down. If that doesn’t work, disconnect from the Internet, delete the web site from History,open Safari, and then reconnect to the Internet. See link for other suggestions.

Safari -Tech support scam pop-ups