High Sierra crashes when not in safe mode

I'm running MacOs High Sierra 10.13.6 on a Macbook Pro Retina from mid 2014

When running the computer in safe mode, I have graphics issues. Specifically, running Chrome and Spotify (with GPU acceleration enabled) leads to unusable products (flickering and jolting screens) - disabling GPU acceleration improves the situation but still shows signs of graphics problems. Lots of flickering, and very poor graphics response.

In non-safe mode the same problems aren't present but opening Chrome or Spotify leads to almost immediate crashes. I also have mds_stores processes running at ever-increasing speed until the laptop is very hot. Eventually in both of the above cases, the computer screen goes to black, and a few seconds later the computer shuts down.

So far I've tried resetting PRAM and the SAC but with no improvement.

Thanks!

p.s. this is the Etre report:

EtreCheck version: 4.3.6 (4D041)

Report generated: 2018-09-16 00:49:27

Download EtreCheck from https://etrecheck.com

Runtime: 2:57

Performance: Excellent

Problem: Computer is restarting

Description:

When running the computer in safe mode, I have graphics issues. Specifically, running Chrome and Spotify (with GPU acceleration enabled) leads to unusable products (flickering and jolting screens) - disabling GPU acceleration improves the situation but still shows signs of graphics problems.

In non-safe mode the same problems are present, but I also have mds_stores processes running at full speed until the computer screen goes to black, and a few seconds later the computer shuts down.

Major Issues:

Anything that appears on this list needs immediate attention.

No Time Machine backup - Time Machine backup not found.

Minor Issues:

These issues do not need immediate attention but they may indicate future problems.

High battery cycle count - Your battery may be losing capacity.

Unsigned files - There are unsigned software file installed. They appear to be legitimate but should be reviewed.

32-bit Apps - This machine has 32-bits apps that may have problems in the future.

Abnormal shutdown - Your machine shut down abnormally.

Hardware Information:

MacBook Pro (Retina, 15-inch, Mid 2014)

MacBook Pro Model: MacBookPro11,2

1 2.2 GHz Intel Core i7 (i7-4770HQ) CPU: 4-core

16 GB RAM - Not upgradeable

BANK 0/DIMM0 - 8 GB DDR3 1600 ok

BANK 1/DIMM0 - 8 GB DDR3 1600 ok

Battery: Health = Normal - Cycle count = 934

Video Information:

Intel Iris Pro - VRAM: 1536 MB

Color LCD

Drives:

disk0 - APPLE SSD SM0256F 251.00 GB (Solid State - TRIM: Yes)

Internal PCI 5.0 GT/s x2 Serial ATA

disk0s1 - EFI (MS-DOS FAT32) [EFI] 210 MB

disk0s2 250.79 GB

disk1s1 - Macintosh HD (APFS) 250.79 GB (176.46 GB used)

disk1s2 - Preboot (APFS) [APFS Preboot] 250.79 GB (25 MB used)

disk1s3 - Recovery (APFS) [Recovery] 250.79 GB (519 MB used)

disk1s4 - VM (APFS) [APFS VM] 250.79 GB (1.07 GB used)

Mounted Volumes:

disk1s1 - Macintosh HD 250.79 GB (72.57 GB free)

APFS

Mount point: /

Encrypted

disk1s4 - VM [APFS VM] 250.79 GB (72.57 GB free)

APFS

Mount point: /private/var/vm

Network:

Interface usbmodem1411: Arduino Uno

Interface en3: USB Ethernet

Interface en0: Wi-Fi

802.11 a/b/g/n/ac

One IPv4 address

Interface en5: USB 10/100/1000 LAN

Interface en4: Bluetooth PAN

Interface bridge0: Thunderbolt Bridge

iCloud Quota: 4.32 GB available

System Software:

macOS High Sierra 10.13.6 (17G65)

Time since boot: Less than an hour

System Load: 3.55 (1 min ago) 4.21 (5 min ago) 2.36 (15 min ago)

Security:

Unsigned Files:

Launchd: /Library/LaunchDaemons/com.oracle.java.Helper-Tool.plist

Executable: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin/Contents/Resources/Helper-Tool

Details: Exact match found in the whitelist - probably OK

Launchd: /Library/LaunchDaemons/org.virtualbox.startup.plist

Executable: /Library/Application Support/VirtualBox/LaunchDaemons/VirtualBoxStartup.sh restart

Details: Exact match found in the whitelist - probably OK

Launchd: ~/Library/LaunchAgents/homebrew.mxcl.postgresql.plist

Executable: /usr/local/opt/postgresql/bin/postgres -D /usr/local/var/postgres

Details: Exact match found in the whitelist - probably OK

Launchd: /Library/LaunchDaemons/com.intel.haxm.plist

Executable: /Library/Extensions/intelhaxm.kext/Contents/Resources/haxm_start.sh

Details: Exact match found in the whitelist - probably OK

Launchd: /Library/LaunchAgents/com.oracle.java.Java-Updater.plist

Executable: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin/Contents/Resources/Java Updater.app/Contents/MacOS/Java Updater -bgcheck

Details: Exact match found in the whitelist - probably OK

Launchd: ~/Library/LaunchAgents/com.github.facebook.watchman.plist

Executable: /usr/local/bin/watchman --foreground --logfile=/usr/local/Cellar/watchman/3.3.0/var/run/watchman/***.log --log-level=1 --sockname=/usr/local/Cellar/watchman/3.3.0/var/run/watchman/*** --statefile=/usr/local/Cellar/watchman/3.3.0/var/run/watchman/***.state

Details: Exact match found in the whitelist - probably OK

32-bit Applications:

7 32-bit apps

Kernel Extensions:

/Library/Application Support/VirtualBox

[Loaded] VBoxDrv.kext (Oracle America, Inc., 5.1.8)

[Loaded] VBoxNetAdp.kext (Oracle America, Inc., 5.1.8)

[Loaded] VBoxNetFlt.kext (Oracle America, Inc., 5.1.8)

[Loaded] VBoxUSB.kext (Oracle America, Inc., 5.1.8)

/Library/Extensions

[Loaded] intelhaxm.kext (6.0.3 - SDK 10.9)

System Launch Agents:

System Launch Daemons:

Launch Agents:

Launch Daemons:

User Launch Agents:

User Login Items:

Flux Application (Michael Herf - installed 2018-05-01)

(/Applications/Flux.app)

Spectacle Application (Eric Czarny - installed 2016-12-24)

(~/Downloads/Spectacle.app)

StartUpHelper SMLoginItem (Spotify - installed 2018-09-14)

(/Applications/Spotify.app/Contents/Library/LoginItems/StartUpHelper.app)

Internet Plug-ins:

JavaAppletPlugin: (installed 2016-11-14)

QuickTime Plugin: (installed 2018-07-19)

Silverlight: (installed 2015-10-29)

User Internet Plug-ins:

AddLive_v3: (installed 2016-02-12)

Picasa: (installed 2014-08-12)

3rd Party Preference Panes:

Java (installed 2016-11-14)

Trusteer Endpoint Protection (installed 2018-04-07)

Time Machine:

Time Machine Not Configured!

Top Processes by CPU:

Top Processes by Memory:

Top Processes by Network Use:

Top Processes by Energy Use:

Virtual Memory Information:

Software Installs (past 30 days):

Diagnostics Information (past 7 days):

2018-09-16 00:41:40 Last Shutdown Cause: -128 - Unknown

2018-09-15 23:51:43 mdworker CPU

/System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/Metadata .framework/Versions/A/Support/mdworker

2018-09-14 21:38:35 Spotlight.app Crash

/System/Library/CoreServices/Spotlight.app

2018-09-14 18:57:18 Firefox.app CPU

/Applications/Firefox.app

End of report