Do you have a complete and current backup? If not, I’d shut down, boot from a bootable installer on USB, boot from the recovery partition, or would use another Mac if you have the right combination of hardware for Target Disk Mode with this Mac, and I’d get a complete backup. Disk Utility to an external disk. Sometimes that’s the recovery path, too.
As I mentioned, sometimes the usage display is skewed, and rebuilding Spotlight can sometimes clear that. To poke around at usage with different tools, see below.
https://support.apple.com/en-us/HT201716
If this is a full disk, all sorts of bits of server can start failing, which writes more stuff, which fills more disk, and things get ugly.
So... start by turning off Spotlight. Off. Don’t restart it right now. I’d then reboot through Safe Mode, as that cleans up boot caches and temporary files, and sometimes that’s enough to clear up usage. (Once you’ve gotten some free space, turn Spotlight back on.)
https://support.apple.com/en-us/HT201262
For poking around at usage, df and du are the command line commands to go looking at storage usage. The following two will show the full disk, then a summary of the usage across all directories in the root directory.
df -h /
sudo du -shx /
The man pages will provide a few more details.
If you have add-on anti-malware, add-on anti-virus, add-on cleaners, optimizers, or network-monitoring and security tools, disable those for now (remove them if you can manage it and continue working to resolve this. (Add-on tools have a long history of not doing what they claim or not doing it well, or introducing interesting new and strange behaviors or corruptions, unfortunately.