Given that some users are not experiencing the iTunes 8288 problem, possibly those of us experiencing those errors have an app in common that corrupted iTunes.
Here are my Failed attempts to update beginning Feb 9, 2019:
Citi Mobile 9.14.0 to 9.14.1 failed Feb 9 at 16:07
CVS_caremark 4.44 to 4.45 failed Feb 9 at 16:07
LiftMaster 3.121 to 3.123 failed Feb 9 at 16:08
Star Walk 7.3.1 to 7.3.2 failed Feb 9 at 16:09
Last successful updates as determined by the Trash folder:
Feb 7 20:26 182937298 AccuWeather 11.9.1.ipa
Feb 7 20:25 84699665 Panera Bread 4.5.0.ipa
Feb 7 20:25 40344923 Shortcuts 2.1.3.ipa
Feb 7 20:24 125962563 maps.me 8.6.4.ipa
Feb 7 20:24 139532252 Target 9.37.2.ipa
Feb 7 20:23 216200631 Lumosity 9.53.ipa
Feb 7 20:22 258762608 Harris Teeter 8.11.1.ipa
Feb 7 20:21 52121171 1Password 7.2.7.ipa.fee
Feb 7 20:20 147395360 Walmart 19.5.ipa
Feb 7 20:19 121876881 Home Depot 5.17.ipa
Note: I don't allow update of 1Password 7.2.5 to 1Password 7.2.7
I update all apps but 1Password by deleting the app in iTunes until all updates complete,
then copy 1Password 7.2.5.ipa to the iTunes Library list.
Something new with this problem is that iTunes Sync with my devices no longer updates Library with apps purchased on the device. I think it always asked me in the past. I have current copies of the apps that failed iTunes updates on my devices. I deleted those apps in iTunes thinking that Sync would update iTunes.