This is the official word from Epson...https://epson.com/faq/SPT_BIGSUR-NS~faq-0000cfc-macos_11?faq_cat=faq-topFaqs
I was on the phone with them for an hour and a half trying to figure out the trouble to no avail. They escalated my incident to developers in Japan and they requested some system info, and ultimately got back to me with this email -
"Thank you for contacting Epson regarding your Epson Artisan 50.
Our team was requesting information about your system previously.
However. our support team has stated that there is a "Missing USB Class Driver" message on some of the older printer models connected via USB. This is an issue with Apple's Big Sur MacOS.
Apple will be releasing an update to fix this problem.
Unfortunately, the only workaround for this is to try to use Apple's Airprint driver. This model does not support Airprint since it is an older/discontinued model.
You would have to wait for Apple ot release an update to fix this issue or use the printer on an older MacOS.
We take your satisfaction seriously and hope that we have helped resolve your issue. If you receive a survey from us, we would greatly appreciate if you could take a few minutes to provide us with feedback about your support experience. Your ratings and comments are extremely important to us.
If this did not resolve your issue, please reply to this email for further assistance. If you have a different support issue, submit a request via our U.S. or Canada Support Site and we will respond in a timely manner.
Thank you again for contacting Epson."