"iTunes Cannot Run Because Some of its Required Files are Missing"

The only option that seems to work is to uninstall version 12.12, install older version https://support.apple.com/kb/DL1816?viewlocale=en_US&locale=en_US which will not like your old library but if you Apple Software update and update ONLY to 12.11 it will work. IGNORE the 12.12 update and other updates until the situation is resolved by Apple.

I have the same problem. To give more detail, this is with iTunes version 12120.6.54012.0 downloaded from the Microsoft Store on 21st September 2021. It appears to be a critical bug in the new version. Apple will need to release a fix in a newer version, I do not believe there is any user workaround for this.

If you uninstall the 12.12 (latest version) fully, then reinstall version 12.10.11 (available here : https://support.apple.com/kb/DL2065?viewlocale=en_US&locale=en_US), everything goes back to normal, your library, settings etc... That's what i did on my Windows 10 (French Language) when i got this pesky error.

As advised by @daletur328, JUST IGNORE the 12.12 it doesn't work right now.

Same here, but I got a new install file directly from Apple (not from Windows Store).

When the install finished, it did ask to update the iTunes. My answer was no, and all works fine.

Link to the install file that I used:

https://support.apple.com/en-us/HT210384

it's work for me

microsoft say :

in french :

, j’utilise également Windows

10 pc et membre de la communauté comme vous. Travaillons ensemble pour régler

ce problème.

Essayez de désinstaller complètement Itunes à l’aide du programme de

désinstallation de Revo, accédez à ce lien ci-dessous pour télécharger

l’application.

https://www.revouninstaller.com/download-profes...

-Une fois téléchargé et installé, cliquez sur Désinstallation forcée

-Rechercher ou rechercher les Itunes

-Cliquez sur Suivant pour le désinstaller complètement.

Une fois cela fait, redémarrez votre ordinateur et réinstallez l’application

Itunes en utilisant ce lien ci-dessous.

https://secure-appldnld.apple.com/itunes12/001-...

Une fois téléchargé et installé, redémarrez votre ordinateur et vérifiez.

Thanks, my language is set to English, but UK-English not US-English.

Bit of a diversity fail if they only tested it in US-English, although we have similar bugs int he application I develop at work, so I guess I shouldn't be too critical. ;-)

The good news is that with this much attention, I suspect a fix is on it's way soon.

I believe you can also change you language settings in Windows to English (United States), reboot and install iTunes from windows store and it will also work.

I tried this and it did work, however I don't want run my PC with language set to English (United States)

I changed all my Windows language settings from 'English (United Kingdom)' to 'English (United States)', signed out and back in again, and then iTunes opened. No need to uninstall or reinstall. It's a crazy bug that the Microsoft store pushed onto the iTunes app.

I can't uninstall iTunes. It does not appear on my programme listing in control panel, and the target file looks really strange - no location on my PC. I have deleted Bonjour and software support, but the installer won't run - says iTunes already installed an must be installed before I can re-install.

How can I delete the current (non-working) version!

Same with me. Apple Support explains how to uninstall iTunes completely (you need to uninstall all other apps from Apple). I did what they say, but when I try to install any other version of iTunes (even the 12.12, including 12.6.3, 12.4.3 and 12.11.4.15) the installer says that I have a newer version installed and stops. And when I enter the Microsoft store to download iTunes installer, there's a message that says that "iTunes no está disponible actualmente" (iTunes is not available in this moment). It seems Microsoft knows what's happening and has canceled the iTunes downloads by now.

This morning (23rd September) Apple pushed a new version of iTunes for Windows via the Microsoft store that appears to fix the problem. Suggest you try upgrading to version 12121.1.54014.0. It worked for me, good luck! :-)

Thank you very much for the post above. I changed the language settings from English ( UK) to English ( USA), signed out and back again as instructed above. It worked like a dream. My iTunes program is back. Nothing lost. What a relief !

This appears to be a language-related bug. See here.

same for me