Major Issues:
Anything that appears on this list needs immediate attention.
Kernel panics - This system has experienced kernel panics. This could be a sign of hardware failure.
This can be a cause for concern.
System Extensions:
[Not Loaded] SymantecEndpointSecurity - version 9.0.5 (Symantec - 2021-08-07)
Application: /Volumes/M*****k/A**********s/Norton Internet Security.app - version 9.0.9 (Symantec - 2021-08-07)
Description: [placeholder]Symantec Endpoint Security system extension[placeholder]
This is ****. Uninstall all symantec "security" stuff.
Effective defenses against malware and other threats
Kernel Extensions:
/Applications/Toast 17 Titanium/Live Screen Capture.app
[Not Loaded] Soundflower.kext - com.Cycling74.driver.Soundflower (1.6.7 - SDK 10.7)
/Applications/iSkysoft iMedia Converter Deluxe.app
[Not Loaded] SystemAudioRecorder.kext - com.Perfect.Driver.SystemAudioRecorder (1.1.0 - SDK 10.6)
These and others are very old system extensions, dating back from even the Snow Leopard era.
You should try removing unnecessary external drives, and installing a clean system on a separate drive (very preferably an SSD, otherwise booting will be sloooooooooow). I expect that running from a clean system will work fine.
Ultimately, after establishing the benefits of a clean system, you may want to make sure to have full backups, and then erase and install on the internal. After that, do not migrate applications, settings, or other files; only the user accounts.