Many thanks for your help. Here is the Etrecheck report.
EtreCheckPro version: 6.6 (66014)
Report generated: 2022-05-01 15:45:41
Download EtreCheckPro from https://etrecheck.com
Runtime: 3:16
Performance: Excellent
Problem: Other problem
Description:
Computer does not shut down properly and reports an error on start up.
Computer frequently does not boot up properly unless I disconnected a
few peripherals first. (Top menu bar with Apple icon does not appear
and hard wired keyboard will not work.
Major Issues:
Anything that appears on this list needs immediate attention.
Unsigned files - There are unsigned software files installed that could be malicious and should be reviewed.
Kernel panics - This system has experienced kernel panics. This could be a sign of hardware failure.
Minor Issues:
These issues do not need immediate attention but they may indicate future problems or opportunities for improvement.
More than one antivirus app - This computer has multiple antivirus apps installed.
Clean up - There are orphan files that could be removed.
Unsigned files - There are unsigned software files installed. These files could be old, incompatible, and cause problems. They should be reviewed.
System modifications - There are a large number of system modifications running in the background.
x86-only Apps - This computer has x86-only apps might not work on future versions of the operating system.
Kernel extensions present - This computer has kernel extensions that may not work in the future.
Sharing enabled - This computer has sharing services enabled that could be a security risk.
Hardware Information:
Mac Pro (Late 2013)
Mac Pro Model: MacPro6,1
3.7 GHz Quad-Core Intel Xeon E5 (Xeon(R)) CPU: 4-core
32 GB RAM - Upgradeable
Video Information:
AMD FirePro D300 - VRAM: 2 GB
Thunderbolt Display 2560 x 1440
AMD FirePro D300 - VRAM: 2 GB
Drives:
disk0 - APPLE SSD SM1024G 1.00 TB (Solid State - TRIM: Yes)
Internal PCI 5.0 GT/s x4 Serial ATA
disk0s1 - EFI (MS-DOS FAT32) [EFI] 210 MB
disk0s2 [APFS Container] 1.00 TB
disk1 [APFS Virtual drive] 1.00 TB (Shared by 6 volumes)
disk1s1 - Macintosh HD - Data (APFS) [APFS Virtual drive] (Shared - 728.82 GB used)
disk1s2 - Preboot (APFS) [APFS Preboot] (Shared - 558 MB used)
disk1s3 - Recovery (APFS) [Recovery] (Shared - 1.11 GB used)
disk1s4 - VM (APFS) [APFS VM] (Shared - 1 MB used)
disk1s5 - Update (APFS) (Shared - 10 MB used)
disk1s6 (APFS) [APFS Container] (Shared - 15.19 GB used)
disk1s6s1 - Macintosh HD (APFS) [APFS Snapshot] (Shared - 15.19 GB used)
disk2 - SanDisk Extreme 55AE 2.00 TB (Solid State - TRIM: No)
External USB 5 Gbit/s USB
disk2s1 - EFI (MS-DOS FAT32) [EFI] 210 MB
disk2s2 [APFS Container] 2.00 TB
disk3 [APFS Virtual drive] 2.00 TB (Shared by 1 volumes)
disk3s2 - T**********2 (APFS) (Shared - 1.59 TB used)
disk4 - PNY USB 3.0 FD 123.82 GB
External USB 480 Mbit/s USB
disk4s1 - J*****E (MS-DOS FAT32) 123.81 GB (1.04 GB used)
Mounted Volumes:
disk1s1 - Macintosh HD - Data [APFS Virtual drive]
1.00 TB (Shared - 728.82 GB used, 270.44 GB available, 254.45 GB free)
APFS
Mount point: /System/Volumes/Data
disk1s2 - Preboot [APFS Preboot]
1.00 TB (Shared - 558 MB used, 254.45 GB free)
APFS
Mount point: /System/Volumes/Preboot
disk1s4 - VM [APFS VM]
1.00 TB (Shared - 1 MB used, 254.45 GB free)
APFS
Mount point: /System/Volumes/VM