Extreme lag and beachballs on Monterey

More than one antivirus app - This computer has multiple antivirus apps installed.

Antivirus software: Apple, CleanMyMac, and Malwarebytes

Cleanmymac is considered malware around here.

You should absolutely uninstall it, then post another report to make sure it is completely gone.

In many cases, macs affected by this **** require a clean install. Fortunately, with Big Sur and Monterey, the system volume is sealed, so it can't be modified.

You should not have MalwareBytes running all the time, only run it manually in case there is a reason to - which, with a well taken care of mac, is usually never.

This post by one of the most respected members of this community should be read everyone who cares about keeping their macs safe and secure:

Effective defenses against malware and other threats

Download and run Etrecheck.  Copy and paste the results into your reply. Etrecheck is a diagnostic tool that was developed by one of the most respected users here in the ASC and recommended by Apple Support  to provide a snapshot of the system and help identify the more obvious culprits that can adversely affect a Mac's performance.

Copy the report

and use the Additional Text button to paste the report in your reply.

Then we can evaluate the report to see if we can determine the cause of the problem.

Your mac has a Fusion Drive, and to make matters worse, one with only a 28GB SSD part.

You should consider getting yourself an external SSD connected via USB3, and use it to boot your mac. The difference will be very noticeable.

You also have many extensions, agents and daemons that are very old - using 10.5 and 10.6 SDK.

Some of those are known not to be compatible with Monterey.

It is clear that you have been upgrading in place, and across macs, for several years, probably a decade or more.

It is high time to do a clean install, followed by the migration of ONLY the user accounts.

Opps. Missed the report at the top of the first post.