is it possible to change the Itune file backup location to another drive instead of C

Yes, we understand what you want to do. Here is the information javaliga was directing you to:

See Relocate iOS device backups. Review the rest of the Make a split library portable user tip for advice on organizing the library on secondary or external storage. Once the backup data has been relocated in this fashion it still appears to be on the C: drive, because that is the path iTunes will continue to use, but files stored in the folder actually live in the alternate location you've linked to. Note that iTunes still checks for free space on drive C: so if your backup is going to take 20Gb of storage you must have that free on the C: drive even though the data ends up on D:.

tt2

See the 'Find backups stored on your Mac or PC' section in:

Locate backups of your iPhone, iPad, and iPod touch - Apple Support

"Though you can copy the Backup folder, you should never move it to a different folder, external drive, or network drive."

Also see turingtest2's reply to:

iTunes Backup Still Using C Drive After I… - Apple Community