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Macos Sequoia 15.0 and office 365 - not responding

Since installing macOS Sequoia (15.0), I've had a problem when I open a Microsoft Word, Excel and PowerPoint file with Office 365 (latest version 16.89). The application doesn't respond. I have to force it to quit and open again: MS Word opened the file correctly. I've reinstalled Office several times, but the problem persists. In general, I can open one file, then application not responding.

Mac Studio, macOS 14.7

Posted on Sep 25, 2024 7:49 AM

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Question marked as Top-ranking reply

Posted on Oct 2, 2024 6:43 PM

This worked for me: Open the Terminal and run the following commands:

/System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/LaunchServices.framework/Versions/A/Support/lsregister -kill -r -domain local -domain system -domain user 


sudo /System/Library/Frameworks/CoreServices.framework/Frameworks/LaunchServices.framework/Support/lsregister -kill -seed -lint -r -f -v -dump -domain local -domain system -domain user -domain network


killall Dock


48 replies
Question marked as Top-ranking reply

Oct 2, 2024 6:43 PM in response to PhMil

This worked for me: Open the Terminal and run the following commands:

/System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/LaunchServices.framework/Versions/A/Support/lsregister -kill -r -domain local -domain system -domain user 


sudo /System/Library/Frameworks/CoreServices.framework/Frameworks/LaunchServices.framework/Support/lsregister -kill -seed -lint -r -f -v -dump -domain local -domain system -domain user -domain network


killall Dock


Oct 31, 2024 7:20 PM in response to PhMil

Since the latest MacOS Sequoia 15.0 upgrade for the past few months, this "not responding" situation has made my life ****. Even the latest MacOS Sequoia 15.1 doesn't change that nightmare situation. Don't know who is responsible for this; Apple or Microsoft, but we end users are victims :-( Please Help!

Oct 4, 2024 1:48 AM in response to marcracred190

Same issue still persists for me as well. I can open documents, but cannot save or save as or even close down the application other than forcing it to stop. I saw an update for Sequoia 15.0 run this morning, so I thought it would be a patch, but the issue is still there, I have reinstalled the full OFC365 for Business package again, still no joy.


My question is this: does the Apple software developer team not test these out - does the fact that the majority of business users use OFC365 not give it enough weight for proper beta testing before rolling out a new OS version?

Sep 28, 2024 5:52 PM in response to PhMil

Same problem here--on Office for Mac Version 16.89.1 and just upgraded for Sequoia 15.0. I get the spinning pinwheel when I try to open Word and PPT files. No difference if I open from the Finder or Word or PPT itself. Then have to force quit the Finder and/or Word or PPT and try again. Eventually it works but I cannot determine why or why not. Really frustrating as this is a basic function.

Sep 30, 2024 10:02 AM in response to PhMil

I was just on a live chat with Microsoft about this problem. They told me to reinstall. I mentioned this and other forums, and that reinstalls were not solving the problem. The response was essentially that it was the fault of Apple. I mentioned that perhaps they needed an update of their own to be compatible. I was told that because Apple has a closed system, there are often compatibility issues with Macs. Here's an idea: disclose that when you're asking people to pay for a Microsoft 365 subscription. We ended the chat with the rep telling me that now that they are aware of the problem, they will look for a speedy solution.

Oct 3, 2024 8:45 AM in response to BahadirT

I found my OWN SOLUTION

It cost me new Mac Office 2021.

When you try to open those idle .xlsx or .docs files, "choose app" section, there is "recommended apps" tab.

I can't choose MS Office Excel and Word.

Change "recommended apps" into "All apps" and tick apply all

you will start to open all your files on your laptop.

I cant send you pictures for that

But I can do that later


Oct 6, 2024 12:18 PM in response to PhMil

Problem solved , install a new copy of Sequoia 15.01 this morning , and first , the widgets are back, and then excel, Power point and Word, works just fine, it takes me a couple of hours, a pen drive with sequoia 15.01 installer and the problems was solved by me , without the support of Microsoft ( they don´t care about this issue ), hope you guys solved this issue with my recommendation

Macos Sequoia 15.0 and office 365 - not responding

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