Macos Sequoia 15.0 and office 365 - not responding

Since the latest MacOS Sequoia 15.0 upgrade for the past few months, this "not responding" situation has made my life ****. Even the latest MacOS Sequoia 15.1 doesn't change that nightmare situation. Don't know who is responsible for this; Apple or Microsoft, but we end users are victims :-( Please Help!

Thank you for this. I tried to do "open with" and did indeed see that "recommended apps" was the option. I changed that to "all apps" and opened the app. I was hopeful that this would magically address my problem too which is not actually opening files but saving a copy (and saving new files as well), but, alas, it did not.

Please keep the suggestions coming folks. This is a horrible experience for everyone - and I just got my first Mac in decades right before the update, not a good way to start a renewed relationship. ugh

Apple and Microsoft are fierce competitors, and do whatever it takes to make life miserable for each other's users. This beachball thing on Sequoia 15.1 is horrifying, but I'm sure Tim is cheering the bad code on .

Apple test Office? LOLOLOL

Problem is back after 30 days on the new user, reinstalled Mac OC Sonoma, another sympthon is Mail working very strange , if you click on an email, the dot stills as unread on blue, I have no Widgets again , and also Office 365 Excel, Powerpoint, and word are freeze , after almost 60 days after Sonoma begins to be adopted, the problem stills the same, I hope that  resolve this issue for us, I've been never have this problem before

And why would Apple be responsible for a third party’s software to remain compatible. And for the vast majority there simply is no problem. I and running macOS 15.1.1 and Microsoft 365 version 16.91 with absolutely no problems.

Absolutely none of the suggestions below have helped. Constant beachball in all Office products. All the standard helpdesk script options have been exhausted, most of the 'delete these files' options have not work. (the ones I didn't try is because the folders suggested are not on my Mac). I'm at the point of a re-image.

Hello Everyone,

I hope you’re all doing well.

As not everyone seems to be experiencing these issues, I’m wondering if it could be related to specific security settings in Exchange, Office 365, or other company-specific configurations.

I’ve tested various solutions — updating, reinstalling, and troubleshooting extensively — but I always end up at the same problem: Excel, PowerPoint, or even Outlook suddenly stop working.

On top of that, I’m also facing similar issues with Adobe Creative Cloud on macOS 15.2, where some apps freeze or crash unexpectedly.

Has anyone else encountered these problems? Could it be that macOS 15.2 is one of the more problematic versions from Apple?

Also, if anyone has found a good repair tool or workaround to fix these issues, I’d love to hear about it. A reliable repair tool that could address these bugs would be extremely helpful.

Looking forward to your suggestions and insights!

Thx for any help

@microsoft you are welcome to fix the issue :)

Other than contacting Microsoft, I have no solution for you.

I have Office 2021 for Mac Home and Business installed on Sequoia v15.0 and all of the 16.89.1 applications work just fine.

I am running macOS Sequoia on Mac Studio and Microsoft 365 ver 16.89, no problem opening word & excel files.

I have the same issue. My Powerpoint, Excel, word all of them are crashing. I am not able to perform any work. Not able to find an easy way to downgrade. Very frustrating.

Same problem here. Very frustrating

so frustrating, I´m working on office web , Microsoft don´t care about it , please let us know when a solution arrives

they don´t care about it, they send you to clean the cache, that doesn't work, is so frustrating this issue, this is my fifth day with the problem, and nobody resolves