Macos Sequoia 15.0 and office 365 - not responding

This worked for me: Open the Terminal and run the following commands:

/System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/LaunchServices.framework/Versions/A/Support/lsregister -kill -r -domain local -domain system -domain user 

sudo /System/Library/Frameworks/CoreServices.framework/Frameworks/LaunchServices.framework/Support/lsregister -kill -seed -lint -r -f -v -dump -domain local -domain system -domain user -domain network

Safari v18, definitely "breaks" O365 online...on the other hand, Teams online, has been in "Preview" mode for Safari, for years, many years.???

Oddly, Google's online app get along well with Sequoia / Safari 18.???

Microsoft is pushing Microsoft Edge, Bing and Copilot...coincidence? If you want seamless compatibility with O365 online, use Microsoft's Edge browser.

Same problem. I was fine until I installed the .0.1 version.

However, I did set up a new user account and everything is fine there, so I wonder if it really is a general compatibility issue with Sequoia/O365 or some file or process that wasn't replicated when I created the new user.

Thanks, but a lot of us have tried this without success.

Similarly for the suggestion to do a factory reset - like setting up a new user account but even more of a pain eg what do you restore from - if it's a Time Machine backup you run the risk of reinstalling the same problem since no-one seems to know what causes the problem.

I'm not familiar enough with Terminal so can someone tell me if running these commands could also affect the new user account I set up where I'm not having the same problem? I'd hate to do this only to discover that one had somehow got "infected" too.

And are these separate commands to be run sequentially or do I just paste the entire set into Terminal?

Thanks

I understand your concern. In my case, I didn’t restore any files from Time Machine for exactly that reason — I didn’t want to risk reinstalling the same issue. Fortunately, all my Word documents were already saved in OneDrive, so I didn’t lose any data. As for the apps, I reinstalled everything from scratch, which seemed to prevent any old issues from reappearing. It’s definitely a bit of a hassle, but in my situation, it was worth it since Office 365 started working properly again after the reset.

I tried running those Terminal commands, but unfortunately, they didn’t work for me. The issue persisted, and I still had to go through the factory reset to get Office 365 to function properly. Thanks for the suggestion, though!

So I really have to stop worrying about this issue since a new user account works just fine, but I thought I would throw this one out for others to try. I had to restore my original user account from Time Machine for an unrelated reason, and by some miracle I no longer have the issue with Word!

To be clear, this was a TM backup that I made this morning, when the old user account definitely still had the problem. So go figure.

After updating to macOS 15.1, my Microsoft 365 stopped working again. Unfortunately, I had to go through the factory reset process once more, followed by a complete reinstallation, to get it working properly.

For reference, I’m using an Apple M1 Pro with 32 GB of RAM. It seems like resetting to factory settings is the only reliable solution so far, but it’s definitely a hassle.

This happened to me too. Finally I fix this by factory reset my Mac and reinstall the MS office and adobe creative suite. Not ideal but this is the last resort, at least I can use my Mac again for work.

1. Don't use Office 365, use Keynote, Pages, iMovie, Garageband and Numbers.
2. Update the Office 365.
3. Reinstall the Office 365
4. Use Convertio to convert files.

Other than contacting Microsoft, I have no solution for you.

I have Office 2021 for Mac Home and Business installed on Sequoia v15.0 and all of the 16.89.1 applications work just fine.

I am running macOS Sequoia on Mac Studio and Microsoft 365 ver 16.89, no problem opening word & excel files.

Tengo el mismo problema. Lo que he estado haciendo es trabajar en línea el office, las aplicaciones del office en mi Mac se quedan trabadas y tengo que forzar el cierre.