Yes. When doing "Get Info" there is a significant difference in what shows under the "More Info" section.
That's not at all surprising, as Nikon Transfer has the ability to add information to the files metadata as the files are copied.
On "dragged and dropped" with the Finder files the following shows:
Dimension
Device Make
Device Model
Color space
Color Profile
Focal Length
Alpha channel
Red eye
F number
Exposure Program
Exposure time
On files copied with Nikon Transfer three additional fields show:
Description
City
State or Province
Those three additional fields match information from preferences edited in Nikon Transfer. Nikon Transfer preferences includes several other possible fields. Several fields that I used in Nikon Transfer don't show up in the finder info but do show on the info tab of Aperture's "Inspector"
I also did a "Get Info" on files still on the memory card. The fields that show were:
Title
Headline
Last opened
Title and Headline were both the camera assigned file name, including the extension.