ITunes can't connect after update to iOS10 - invalid response

Do you have any Anti-Virus or firewall software on your mac?

Version 10.7.5.

No Anti-virus software but firewall, yes as this is my work computer (which has never caused any problems in the past).

Can you disable the firewall? I know Kaspersky has had issues in the past with this, it's something about the firewalls blocking secure connections. You can re-enable it after it is done updating/syncing.

I have the same problem. I'm just starting but before taking out iTunes and reinstalling I want to be able to restore my phone with the previous iOS. Will I lose that if I reinstall? (I wouldn't do it, but the 3D button is completely missing from my phone.) But now that I can't connect anyway...

So where do you find a new iTunes to install? I've upgraded to IOS 10 on one of our iPhones and it's clearly incompatible with older versions of iTunes. So i'll never upgrade on the other phone. But i'm going to try to delete iTunes on the computer, but where does one get a new version to install?

Thanks.

But the mobile device should have all the new software after the upgrade to IOS 10, no? Where does one fine new "mobile device support software" if not in the OS?

but the iPhone has the most recent software, since it was just upgraded to IOS 10. How can this be something that is not up to date? Seems like the Mac's OS 10.7.5 isn't compatible with IOS 10, and Apple should have warned us that our iTunes is no longer compatible ;-(

They did warn you. It's clearly state in the system requirements.

Yes if one reads it. But since Apple keeps sending those daily reminders to upgrade that lock the iphone till you acknowledge it's easy to give in the pressure to upgrade. I didn't but my wife did and now she can't connect to iTunes and all her music.