Tried this, and having the same problem in safe mode. Once the MacBook Pro begins the process of going to sleep, everything locks up, the fan runs high speed, and powering down the machine is the only way forward. This only happens on my mid-2012 MacBook Pro with Intel Iris Pro 1536MB graphics, and this MacBook Pro is bound to my work domain. I have the same problem when I'm on the domain at work as I do off the domain at home.
I use a personal mid-2012 MacBook pro with Intel HD Graphics 4000 1536 MB, and this person machine is not bound to a domain. No problems on this machine.
I get the same problem when I close the work laptop to move around the office. I have to boot after each lid closing. Killing my productivity.