Thank you for being proactive and going that extra step and suppling the EtreCheck Report.
This computer is running several Security and Antivirus Applications all at the same time
The Important elements of the builtin Security and Updates parts of the Native Apple Operating System are Turned Off leaving the computer compromised.
It is also heavily Modified Operations System
Below are the Key Aspects from the Report and with some suggestions to possible remedy this situation.
Though, to be forwards about this - One may or may not consider stating with a Clean Slate as in Recovery Mode and remove all data and do a Clean and Virginal Installation. This would wipe out the existing issue of where there are many.
If considering this open - do not suggest Migrating anything from a TM Backup except the User Account. Otherwise - one will be reintroducing the Already Existing issue back into a Virginal Installation
Major Issues:
Q - Gatekeeper disabled - Gatekeeper security protection is disabled. This computer is at risk of malware infection.
A - Unless there is a specific reason not to enable this - the computer would be better served by Enabling
Q - Apple security disabled - Apple security software is disabled. This computer is at risk of malware infection.
A - Unless there is a specific reason not to enable this - the computer would be better served by Enabling
Minor Issues:
These issues do not need immediate attention but they may indicate future problems or opportunities for improvement.
Q - Unsigned files - There are unsigned software files installed. These files could be old, incompatible, and cause problems. They should be reviewed.
Q - Old Applications: 227 x86-only apps
A - Self explanatory and the User ( you )will need to evaluate each Application for more current and updated version or replacements
Q - System modifications - There are a large number of system modifications running in the background.
A - Any time an Operating system is so heavily Modified - this places the system in a compromised state with sometime unintended consequences like that which is happen now on the computer
Q - Runaway user process - A user process is using a large percentage of your CPU.
A - This dovetails into and may be directly related to earlier issue on Unsigned files
Q - Kernel extensions present - This computer has kernel extensions that may not work in the future.
A - Refer to later area below regarding " System Extensions "
Hardware Information:
iMac (Retina 5K, 27-inch, 2020)
System Software:
macOS Monterey 12.4 (21F79)
Q - Antivirus software: ESET
A - There are no known Windows-like Viruses in the wild that self replicate and affect macOS, because of the underling UNIX Foundation and Permission Limitation.
The Only thing this Antivirus software is protecting is the Bank Account of the Developers and for zero return to the User aside from the problems this software creates.
Any of the below should be removed as per Developers Instructions
ESET and please take a moment to read what this application can and does do.
The The Built in Security is all that is required.
System Extensions:
Q - [Running] ESET Firewall - version 6.11.100 (ESET, spol. s r.o. - 2022-03-16)
A - Already covered this in above
Q - Application: /Applications/ESET Cyber Security Pro.app - version 6.11.100 (ESET, spol. s r.o. - 2022-03-16)
A - Already covered this in above
Kernel Extensions:
/Applications/ESET Cyber Security Pro.app
A - Already covered this in above on ESET
Q - [Running] Kaspersky Secure Connection Login Item (App Store - installed 2022-05-26)
A - Search - Apple Community https://discussions.apple.com/search?q=%20Acronis%20Cyber%20Protect%20Connect%20Agent&page=1&content=filterDiscussions
Software Installs (past 60 days): Install Date Name (Version)
Q - 2022-05-03 Acronis Cyber Protect Connect Agent (1.0.0)
A - https://discussions.apple.com/search?q=%20Acronis%20Cyber%20Protect%20Connect%20Agent&page=1&content=filterDiscussions