1—Your drive speeds are 1/2 of nominals, likely suffering from CleanMyMac:
Performance:
System Load: 1.33 (1 min ago) 1.41 (5 min ago) 1.42 (15 min ago)
Nominal I/O usage: 0.05 MB/s
File system: 18.21 seconds
Write speed: 1061 MB/s ⚠️
Read speed: 2873 MB/s
For that drive model, your Write speeds should be over 2000MB/sec. Example from my 2017 iMac 5K with Apple's factory SSD:
Performance:
System Load: 1.66 (1 min ago) 1.42 (5 min ago) 1.31 (15 min ago)
Nominal I/O speed: 0.23 MB/s
File system: 20.35 seconds
Write speed: 2156 MB/s 👈🏻
Read speed: 2863 MB/s
I have seen plenty of EtreCheck reports where removing CleanMyMac has improved drive Write scores significantly. So you may have paid money to have to your expensive SSD's performance plummet.
Since the year 2000, the macOS has included elegant, automated self-maintenance routines that manage ALL needed cleaning and optimizing without any outsde help. The industry knows this so, to me, any third-party app that claims a Mac needs help with cleaning and and maintenance is a word the forum's profanity filter would remove!😳
Worse, useless scamware interferes the that elegance you paid Apple to build into the OS, causing instability and slowdowns. I been here a painfully long time and had never seen a reprot of a clening app make a Mac run better.
And you probably didn't need the expense of having 48GB RAM installed if CMM is casuing your your slowness.
2—Likewise, evict AntiVirus One.
3—Your SSD is rather small for the load it caries. Make sure it get not fuller tht in tiis now,. Your free space ia ant minmumum.
4—Ancient Plug-ins:
Internet Plug-ins:
Silverlight: 5.1.50901.0 (? - installed 2019-10-05)
Flip4Mac WMV Plugin: 2.4.0.11 (? - installed 2011-11-06)
AdobePDFViewer: 9.0.0 (? - installed 2011-01-30)
iPhotoPhotocast: 7.0 (Apple - installed 2012-03-31)
AdobeAAMDetect: 3.0.0.0 (Adobe Inc. - installed 2024-06-26)
EPPEX Plugin: 3.0.5.0 (? - installed 2009-07-29)
Note that FOUR of these are older that your computer. That means you don't need them. If you do need them, update them, And Silverlight was dead and buried by 2021
5—Can't tell from the report if you have a Time Machine backup set up. If not, you need it for when the small SSD fills up or third-party fearware trashes your drive.