You can’t open the application “Screenshot” because it is not responding.
macOS Mojave ScreenShot app error
iMac with Retina 5K display, macOS Mojave (10.14.1)
Question marked as
Try the Safe Mode.
If it works in the Safe Mode, try running this program when booted normally and then copy and paste the output in a reply. The program was created by Etresoft, a frequent contributor. Please use copy and paste as screen shots can be hard to read. Click “Share Report” button in the toolbar, select “Copy to Clipboard” and then paste into a reply. This will show what is running on your computer. No personal information is shown.