In my opinion, apps like App Tamer are good reasonable patches but they do not solve the problem, they hide it.
Hiding the problem in the long run makes it worse since developers assume their current solution is good enough; so why even bother to fix something that no one has complains. In this thread we have seen that, some people just have that attitude: "Mail is fine because I only have one account... or I don't mind... or use another program, buy another computer, etc.... just stop critics".
This kind of approach is what has caused that even though we have Macs 1000x more powerful than 20 years ago, they consume more and more resources performing the same tasks, like reading emails. People read the same kind of emails (the protocol has almost no changes) 20 years ago on 60Mhz computer. It is unbelievable the amount of resources that an email program uses to perform the same task today just because bad development practices.