I am having this problem with my classroom keyboards (not high end, I know). I am using Yamaha PSR 293 and connect them to iPads using USB-B to lightning. I have been using this with a piano app (Scoove) so my students can work independently and each at their own pace. The iPads that automatically updated to 15.4.1 no longer can be used because the iPad no longer connects via midi. But, the iPads that had not updated still work. I have one newer PSR-E373 that does work with the update. this supports someone else's post that it might be the older midi causing the compatibility problem. Unfortunately, there is no way my school district is going to buy me 10 new keyboards; this is really impacting my curriculum. If anyone discovers some kind of adapter that helps connect the new update to the older midi device, please post!